Endocrine Abstracts

Activated brown adipose tissue (BAT) combusts high amounts of intracellular lipids into heat. In the past few years, we have investigated the consequences of BAT activation for lipid metabolism and cardiometabolic health. Initially, we showed that South Asians, a population characterized by dyslipidemia and prone to develop type 2 diabetes and cardiovascular disease compared to white Caucasians, have low BAT activity correlating with low energy expenditure (Lancet Diab Endocri...

The past decade, epidemiological studies have associated disturbances of the biological clock, as occurs in shift work, with low bone mineral density and increased fracture risk. As a large part of the working population participates in shift work (e.g. almost 30% of workers in the U.S.), this demonstrates the need for further research on the risk of skeletal disorders associated with circadian disturbances. In this study, we aimed to investigate to what extent rhythmicity exi...